PROSTVAC™ data accepted for an oral presentation at the ASCO Annual Meeting
16 April 2009
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Bavarian Nordic announced today that a PROSTVAC™ abstract
has been accepted for presentation at the 2009 American Society of
Clinical Oncology (ASCO) Annual Meeting in Orlando May 29 to June
2, 2009. ASCO is the world's leading cancer organization.
Data from a Phase 2 prospective randomized placebo-controlled study
of 125 patients with advanced prostate cancer will be presented by
Philip Kantoff MD, Professor of Medicine, Harvard Medical School,
and the Dana-Farber Cancer Institute who is the principal
investigator of the study. The presentation will take place on May
30, 2009 at 5:00 PM EDT.
Bavarian Nordic previously reported data from this study, showing
that patients receiving PROSTVAC™ had a statistically
significantly longer median overall survival by 8.5 months
(p=0.015) compared to the control group. Currently the only
approved treatment for advanced prostate cancer extends median
overall survival by an average of 2.4 months. In addition,
PROSTVAC™ also had a very favourable safety and tolerability
profile.
PROSTVAC™ is a therapeutic vaccine moving into late stage
clinical development that has the potential to extend the lives of
people with advanced prostate cancer. Administered subcutaneously,
it induces a specific, targeted immune response that attacks
prostate cancer cells. Conventional chemotherapy currently used to
treat prostate cancer has limited survival rates and is often
associated with numerous side effects. In contrast, PROSTVAC™
has the potential to extend survival with improved quality of life.
PROSTVAC is being developed in collaboration with the National
Cancer Institute under a Cooperative Research and Development
Agreement with Bavarian Nordic's U.S.-based subsidiary, BN
ImmunoTherapeutics.
In clinical trials to date PROSTVAC™ and related PSA
containing poxviral vaccines have been investigated in more than
500 patients for 10 years.
Anders Hedegaard, President & CEO of Bavarian Nordic said:
"We are very pleased that ASCO has accepted the PROSTVAC™
study as an oral presentation at this year's annual meeting. This
is truly encouraging and it solidifies our decision to take
PROSTVAC™ into Phase 3 in 2010 based on the promising data,
that we have already reported with this therapeutic
vaccine."
Contact:
Anders Hedegaard, President & CEO.
Phone: +45 23 20 30 64