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CV301 Publications

Publications on or relating to CV301 (PANVAC or CEA-MUC-1-TRICOM).

Schlom J, Gulley JL

Vaccines as an Integral Component of Cancer Immunotherapy

JAMA. 2018;320(21):2195-2196. doi:10.1001/jama.2018.9511
Foy SP, Mandl SJ, dela Cruz T, Cote JJ, et al.

Poxvirus-based active immunotherapy synergizes with CTLA-4 blockade to increase survival in a murine tumor model by improving the magnitude and quality of cytotoxic T cells

Cancer Immunol Immunother. 2016; 65: 537–549.
Foy SP, Sennino B, dela Cruz T. et al.

Poxvirus-Based Active Immunotherapy with PD-1 and LAG-3 Dual Immune Checkpoint Inhibition Overcomes Compensatory Immune Regulation, Yielding Complete Tumor Regression in Mice

PLoS One. 2016 Feb 24;11(2):e0150084. https://doi.org/10.1371/journal.pone.0150084
Foy SP, Mandl SJ, dela Cruz T, et al.

Magnitude and quality of tumor-infiltrating T cell response upon poxvirus-based active immunotherapy alone and in combination with CTLA-4 immune checkpoint inhibition.

J Clin Oncol. 2014;32:5s suppl: Abstract 3013.
Foy SP, Rountree RB, Joseph Cote J, et al.

Anti-tumor efficacy of poxvirus-based active immunotherapy alone and in combination with reduced doses of multiple immune checkpoint inhibitors.

J Clin Oncol. 2014;32:5s suppl: Abstract 3058.
Mohebtash M, Tsang KY, Madan RA, et al.

A pilot study of MUC-1/CEA/TRICOM poxviral-based vaccine in patients with metastatic breast and ovarian cancer.

Clin Cancer Res. 2011;17:7164-7173.
Gulley JL, Arlen PM, Tsang KY, et al.

Pilot study of vaccination with recombinant CEA-MUC-1-TRICOM poxviral-based vaccines in patients with metastatic carcinoma.

Clin Cancer Res. 2008;14:3060-3069.
Madan RA, Arlen PM, Gulley JL

PANVAC-VF: poxviral-based vaccine therapy targeting CEA and MUC1 in carcinoma.

Expert Opin Biol Ther. 2007;7:543-554.
Arlen PM, Pazdur RM, Skarupa L, et al.

A randomized phase II study of docetaxel alone or in combination with PANVAC-V (vaccinia) and PANVAC-F (fowlpox) in patients with metastatic breast cancer.

Clin Breast Cancer. 2006;7:176-179.